HUST is a comprehensive university with well developed disciplines. Areas of excellence such as national and provincial key disciplines are as follows:
- National Key Disciplines
- Mechanical Engineering
- Optical Engineering
- Material Science and Engineering
- Power Engineering and Engineering Thermo-Physics
- Electrical Engineering
- Control Science and Engineering
- Biomedical Engineering
- National Key Subdisciplines
- Western Economics
- Higher Education
- Bio-physics
- Micro-Electronics and Solid State Electronics
- Computer Architecture
- Hydraulic and Hydropower Engineering
- Pathology and Pathophysiology
- Internal Medicine (Cardiovascular Diseases)
- Internal Medicine (Hematonosis)
- Internal Medicine (Respiratory)
- Surgery (General Surgery)
- Surgery (Urination)
- Gynecology and Obstetrics
- Anesthesiology
- Occupational and Environmental Health
- National Key Disciplines (developing)
- Communication and Information System
- Internal Medicine (Infectious Diseases)
- Imaging and Nuclear Medicine
- Children and Women Health Care
- Combined Therapy of Chinese and Western Medicine
- Pharmacology
- Management Science and Engineering
- Superior Disciplines of Hubei Universities and Colleges
- Western Economics
- Higher Education
- Mechanical Engineering
- Optical Engineering
- Power Engineering and Engineering Thermo-Physics
- Electrical Engineering
- Control Science and Engineering
- Pathology and Pathophysiology
- Surgery
- Gynecology and Obstetrics
- Anesthesiology
- Occupational and Environmental Health
- Distinguishing Featured Disciplines of Hubei Universities and Colleges
- Biophysics
- Materials Processing Engineering
- Micro-Electronics and Solid State Electronics
- Computer Architecture
- Hydraulic and Hydropower Engineering
- Biomedical Engineering
- Internal Medicine
- Key Disciplines of Hubei Province
| Marxism Philosophy | Basic Medicine |
| Theoretical Economies | Internal Medicine |
| Quantitative economics | Pediatrics |
| Sociology | Genealogy |
| Linguistics and Applied Linguistics | Neurology |
| Journalism and Communication | Dermatology and Venereology |
| Physics | Imaging and Nuclear Medicine |
| Polymer Chemistry and Physics | Ophthalmology |
| Biology | Otorhinolaryngology |
| Mechanics | Oncology |
| Architecture Design and Theory | Pharmacology |
| Design and Construction of Naval Architecture | Public Administration |
| Environmental Science and Technology | Business Administration |
| Civil Engineering | Management Science and Technology |
| Electronic Science and Technology | Rehabilitation Medicine and Physical Therapy |
| Information and Communication Engineering | Public Health and Preventive Medicine |
| Computer Science and Technology | Integrated Traditional and Western Medicine |
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Urban Planning and Design (including Landscape Planning and Design) |
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